Extended Data Fig. 2: Intronic editing sites preserve target gene expression.
From: SEED-Selection enables high-efficiency enrichment of primary T cells edited at multiple loci
a, Panel of gRNAs targeting TRAC exon (e1) and TRAC intron (i2–i10); not depicted to scale. b, Assessment of TCR expression by flow cytometry and indel generation by bulk genomic DNA sequencing in T cells after editing with gRNAs depicted in b (n = 2 donors). c, Panel of gRNAs targeting B2M introns; not depicted to scale. d, Assessment of B2M expression by flow cytometry and indel generation by bulk genomic DNA sequencing in T cells after editing with gRNAs depicted in c (n = 2 donors).
