Extended Data Fig. 9: Comparison of complex SVs calls made by different tools. | Nature Biotechnology

Extended Data Fig. 9: Comparison of complex SVs calls made by different tools.

From: Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing

Extended Data Fig. 9

Examples of complex SVs discovered by Severus only and falsely clustered SVs in Jabba and Linx. A. A false complex SV cluster in Linx. B. A large simple deletion was falsely detected as rigma by Jabba. C. Repeat expansion detected as a templated insertion (TIC) in Jabba. D. Breakpoints from different haplotypes clustered together in Jabba. E. An unbalanced translocation detected only by Severus. F. A reciprocal translocation detected as TIC in Jabba. G. A chromoplexy case detected only by Severus.

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