Extended Data Fig. 2: Characterization and verification of inverted Alu pairs.
From: Improved RNA base editing with guide RNAs mimicking highly edited endogenous ADAR substrates
a, An example of the secondary structure of an inverted Alu pair predicted by RNAhybrid. b, Cumulative distribution showing the number of editing sites in each Alu element. c, The proportion of edited and unedited ECSs. d, Editing levels decreased with increasing distances between the two arms of edited inverted Alu pairs. The mean editing level is defined as the average editing level across all Alu editing sites within an inverted Alu pair. Box plots show the median and the 25th and 75th percentiles, with whiskers extending 1.5 times the interquartile range. Sample sizes are provided in the source data. e, The proportion of single Alus and inverted Alus that overlapped with dsRID-identified dsRNA regions.
