Extended Data Fig. 2: Comparison of metatranscriptomic and metagenomic counts for various species across skin sites. | Nature Biotechnology

Extended Data Fig. 2: Comparison of metatranscriptomic and metagenomic counts for various species across skin sites.

From: Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body

Extended Data Fig. 2

Scatter plots of species level metatranscriptomic (RNA) counts expressed as transcripts per million (TPM) against species level metagenomic (DNA) counts expressed as counts per million (CPM). Points on the solid line represent equal proportions of RNA to DNA for a species. The areas beyond the dotted lines represent ≥4-fold differences between RNA and DNA counts. Plots represent data from all 102 paired metagenomes and metatranscriptomes in this study. Note that Staphylococcus (dark blue) and Malassezia (lilac) species have an outsized contribution to metatranscriptomes at most sites despite their lower representation in metagenomes. Data is from the full cohort (n = 24, 23, 19, 18, 18 for scalp, cheek, antecubital fossa, volar forearm and toe web respectively).

Source data

Back to article page