Fig. 4: Scalability of sequence alignment and search tools.
From: Efficient sequence alignment against millions of prokaryotic genomes with LexicMap
Benchmarking BLASTn, COBS, LexicMap, MMseqs2, Minimap2 and Ropebwt3 for both index construction and subsequent querying, using datasets ranging from 1 to 1 million genomes. a, Index size and memory requirements for index construction. b, Search (alignment for BLASTn, LexicMap, MMseqs2, Minimap2 and Ropebwt3 and search for COBS) time and memory use. The query set consists of a rare gene (secY) and a 16S rRNA gene (rrsB) sequence. All tools return all possible matches. Performance data are in Supplementary Tables 7 and 8.
