Extended Data Fig. 7: scHiCAR analysis of mouse skeletal muscle regeneration. | Nature Biotechnology

Extended Data Fig. 7: scHiCAR analysis of mouse skeletal muscle regeneration.

From: Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR

Extended Data Fig. 7

a. UMAP visualizations of mouse muscle cells colored by gene expression for representative marker genes of different cell types as indicated. b. UMAP visualizations of mouse muscle cells colored by gene activity scores (chromatin accessibility) for representative marker genes of different cell types. c. Smoothed spline regression curves of gene expression (top), gene activity (middle), and scA/B value (bottom) of Myog over pseudotime of muscle regeneration. The dashed line marks the pseudotime at which the predicted value is maximal. d. Single-cell contact matrices centered on Myog locus at three selected cells (cell 1, 2, 3) along pseudotime, as marked in Fig. 6k.

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