Supplementary Figure 4: Normal STAT6 activity in lamina propria immune cells from patient 1.
From: Human TGF-β1 deficiency causes severe inflammatory bowel disease and encephalopathy
CyTOF analysis of STAT6 phosphorylation (Tyr641; p-STAT6) in lamina propria mononuclear cells derived from patients without IBD (controls: uninflamed, blue; inflamed, orange), a patient with Crohn’s disease (CD) (green) and P1 (black). Histogram plots show baseline p-STAT6 in live cells that were gated on the indicated populations (left), and the heat map representation depicts the corresponding median expression values (MEV) for p-STAT6.
