Supplementary Figure 6: Effects of ceRBP crosstalk on DEMETER gene solutions.
From: Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics
All shRNAs (~100,000) are grouped into three groups according to values of DEMETER seed solutions shown in Fig. 4a (q1: < 0.2, q2: ≥ 0.2 and < 0.6, and q3: ≥ 0.6), and values of DEMETER gene solution are compared. shRNAs with competitive seeds have significantly lower gene effects in a q1 group. P values (versus no overlap) were calculated by two-sided Wilcoxon signed rank test with Bonferroni correction. n.s.: not significant.
