Supplementary Fig. 9: Genomic alterations in TP53-wild-type WGD-positive tumors.
From: Genome doubling shapes the evolution and prognosis of advanced cancers

The most common genomic alterations in the 1,347 TP53-wild-type WGD-positive tumors are shown including key effectors of E2F-mediated G1 arrest, which account for 31.8% of such tumors (15% when including only those covariates identified as significant in our model; Methods). Alteration types are indicated by the legend (bottom).