Supplementary Fig. 12: αN-catenin mutations do not affect actin ratios in patient neuronal progenitor cells. | Nature Genetics

Supplementary Fig. 12: αN-catenin mutations do not affect actin ratios in patient neuronal progenitor cells.

From: Biallelic loss of human CTNNA2, encoding αN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migration

Supplementary Fig. 12

Western blot of fractionated G- and F-actin from control and affected individuals with CTNNA2 mutation. Densitometry quantification on right. Top box, Q3; bottom box, Q1; median. The whiskers represent the minimum and maximum values observed in the dataset. Repeated with three biological replicates. Two-tailed Student’s t test was used to calculate significance: P = 0.354.

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