Supplementary Figure 14: Accuracy of PrimateAI across different conservation profiles in the genome.
From: Predicting the clinical impact of human mutation with deep neural networks
The x axis represents the percentage alignability of the 51 AA around a sequence with the 99-vertebrate alignments. The y axis represents the classification performance of PrimateAI for variants in each of the conservation bins, benchmarked on the test dataset of 10,000 withheld primate variants.
