Supplementary Figure 2: Missense:synonymous ratios for CpG and non-CpG variants.
From: Predicting the clinical impact of human mutation with deep neural networks

a,b, Missense:synonymous ratios for CpG (a) and non-CpG (b) variants across the human allele frequency spectrum, using all variants from the ExAC/gnomAD exomes. c,d, Missense:synonymous ratios for CpG (c) and non-CpG (d) variants across the human allele frequency spectrum, restricted to only human variants that are identical by state with chimpanzee common polymorphisms.