Supplementary Figure 5: PAR levels determined by western blotting. | Nature Genetics

Supplementary Figure 5: PAR levels determined by western blotting.

From: Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair

Supplementary Figure 5

(a) Western blot image and (b) quantification of total cellular poly-ADP-Ribose (PAR) levels in HEK293FT tumor samples 24 h after treatment with the indicated concentrations of BMN-673. n = 6 replicates; bars represent mean + /- SEM. Statistical analysis by two-sided t-test with df = 10. For a, images were cropped around the known molecular weight of the band of interest. Full blots appear in Supplementary Figure 6.

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