Supplementary Figure 1: Sample details and workflow.
From: Copy number signatures and mutational processes in ovarian carcinoma
a, REMARK diagram of BriTROC-1 samples. b, Analysis workflow. Copy number signatures were initially derived using high-quality samples from 91 patients and then applied to the samples with intermediate quality from 26 more patients; in total, 199 BriTROC-1 samples had copy number signatures assigned. Copy number signature validation was performed across 527 samples from PCAWG-OV and TCGA. The number of samples analyzed from the three cohorts is shown for each analysis. WGS, whole-genome sequencing; Amp. FBI, amplification-associated fold-back inversion; TDP score, tandem duplicator score.
