Supplementary Figure 2: Example of a germline SNP within the proximity of a somatic SNV. | Nature Genetics

Supplementary Figure 2: Example of a germline SNP within the proximity of a somatic SNV.

From: Accounting for proximal variants improves neoantigen prediction

Supplementary Figure 2

An example from one of the TCGA melanoma samples with a missense SNV that overlaps a germline SNP (dbSNP ID: rs9891498), 21 nucleotides upstream. When translated, the germline SNP results in the S357F (NP_001275708.1:p.Phe357Ser) alteration and is 7 amino acids downstream of the missense somatic variant F350S (NP_001275708.1:p.Ser350Phe) in MARCH10.

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