Supplementary Figure 1: Locus plots for the Icelandic data showing the associations of variants (discovered by whole-genome sequencing of 15,220 Icelanders) at the ALOX15 locus with nasal polyps (n = 1,175).

The leading variant is shown as a purple diamond, and other variants are colored according to correlation (r²) with the leading marker (legend at top-left). –log₁₀P values are shown along the left y-axis (two-sided logistic regression), and correspond to the variants depicted in the plot. The right y-axis shows calculated recombination rates at the chromosomal location, plotted as a solid blue line.