Supplementary Figure 2: Flowcharts depicting bacterial genome and transcriptome data analysis.

(a) Next-generation sequencing data analysis pipeline employed for the preprocessing, read mapping, variant discovery and downstream genomic analyses of whole-genome sequencing data. aMLST: Multilocus sequence type, bSNP: Single nucleotide polymorphism, cHGT: Horizontal gene transfer. (b) Bioinformatics pipeline for demultiplexing, quality assessment, adapter trimming, read mapping, and data normalization and differential expression of transcriptome data.