Supplementary Figure 12: Target cluster enrichment analysis.
From: A genetics-led approach defines the drug target landscape of 30 immune-related traits
a, Forest plot of approved drug targets (grouped by drug indication terms) enriched in cluster C6. The significance level (FDR), odds ratio and 95% CI calculated according to Fisher’s exact test (one-sided). Also illustrated gene lists for each enriched drug indication term. Right: illustration of approved drug targets for immune system diseases found in the cluster, together with diseases and drugs. b, Forest plot of KEGG pathways enriched in target clusters. Lines represent 95% CI (one-sided Fisher’s exact test).
