Supplementary Fig. 10: GWAS enrichment at chromatin accessible sites.

a, Significance of heritability enrichment between samples and complex traits (see Methods). b, Trait heritability enrichment of samples from various lineage and condition classes. Resting samples indicated in blue and stimulated samples in red. Innate cells were excluded. c, Heatmap showing top 100 accessible peaks (y-axis) for lineage clusters (labeled) that are unique for different cell lineages conditions across samples (x-axis). Increasingly accessible regions are colored red corresponding to a larger scaled intensity value (see Methods). d, Definition of peak profiles. Peak profiles are labeled on the y-axis, which are defined by accessibility in various lineage-condition groups on the x-axis. Sample sizes can be found in Supplementary Table 1.