Extended Data Fig. 6: Protein sequence alignment of ACE2 and MIRb-ACE2.

The predicted MIRb-ACE2 translation product is a 459-amino acid protein lacking the indicted single peptide, domains interacting with SARS-CoV spike glycoprotein, but retaining the transmembrane domain. The novel 10-amino acid sequence created by LTR16A1 exonisation is also shown.