Extended Data Fig. 2: Distribution of LT-FH phenotypes for 12 UK Biobank diseases. | Nature Genetics

Extended Data Fig. 2: Distribution of LT-FH phenotypes for 12 UK Biobank diseases.

From: Liability threshold modeling of case–control status and family history of disease increases association power

Extended Data Fig. 2

We plot the distribution of the LT-FH phenotype for each disease. We also report the kurtosis for both GWAS and LT-FH; Pearson’s measure of kurtosis, \(\kappa = \frac{{E\left[ {\left( {X - \mu } \right)^4} \right]}}{{\left( {E\left[ {\left( {X - \mu } \right)^2} \right]} \right)^2}}\), is calculated using the R package moments.

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