Extended Data Fig. 7: Design and evaluation of synthetic unit pairs.
From: Transcription imparts architecture, function and logic to enhancer units
a, Comparison of sub-element activities within synthetic enhancer clusters. The stronger sub-element is always chosen to be e1, and the weaker sub-element is e2. Gray lines indicate approximate significance cut-offs. b, Correlation between individual eSTARR-seq activities tested previously and re-tested as controls in the synthetic fusion screen (n = 48 elements). c, Agreement between predicted and observed cluster activities (‘C’) for enhancer-containing synthetic pairs. d, Agreement between predicted and observed cluster activities (‘C’) for enhancer-less synthetic pairs.
