Extended Data Fig. 6: Predicted vs. observed number of genome-wide significant SNPs at different significance thresholds. | Nature Genetics

Extended Data Fig. 6: Predicted vs. observed number of genome-wide significant SNPs at different significance thresholds.

From: The distribution of common-variant effect sizes

Extended Data Fig. 6

MGWAS was predicted using interim-release UK Biobank summary statistics (maximum N=145k) and evaluated in the full release (maximum N=460k). Squared correlations between predicted and observed values were 0.92, 0.97, 0.92 and 0.91 in panels a-d respectively. In panel d, the data points for several points are superimposed near the origin. For numerical results, see Supplementary Table 2.

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