Extended Data Fig. 1: Mutation burdens in ESCC. | Nature Genetics

Extended Data Fig. 1: Mutation burdens in ESCC.

From: Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

Extended Data Fig. 1

Mutation burdens for SBS, DBS and ID variants show modest differences between countries using the Kruskal-Wallis (two-sided) test (n=552 biologically independent samples). Hypermutators in each group were defined using the interquartile range method, with cases with mutation burdens more than 1.5 IQR above Q3 removed from the analysis. Box and whiskers plots are in the style of Tukey. The line within the box is plotted at the median while the upper and lower ends are indicated 25th and 75th percentiles. Whiskers show 1.5*IQR (interquartile range) and values outside it are shown as individual data points. Countries are ordered by approximate incidence rate in ascending order.

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