Extended Data Fig. 8: Expression and eQTL analysis of 3p21.31 candidate lung effector genes.
From: Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus
a, Genomic position of genes identified as 3p21.31 candidate causal genes with method of identification, including two TWAS10,49. b, GTEx whole lung RNA-seq expression profiles for candidate causal genes as transcripts per million (TPM) with rs17713054 eQTL two-sided P value for lung. For violin plots, minima and maxima are the top and bottom of the violin, black lines show means, ends of the pale regions denote first and third quartiles, and black dots denote outliers. n = 578 independent samples. c, Chromium single nucleus RNA-seq35 from non-diseased adult lung (n = 3), including Alveolar Type 1 (AT1) and Type 2 (AT2) Pneumocytes and Pulmonary Neuroendocrine cells (PNECs).
