Extended Data Fig. 2: Quality control of the snRNA-seq datasets. | Nature Genetics

Extended Data Fig. 2: Quality control of the snRNA-seq datasets.

From: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Extended Data Fig. 2

a, SnRNA-seq data analysis strategy. Prior to data integration, ambient RNA was removed. b, UMAP (uniform manifold approximation and projection) of snRNA-seq data from all tissue samples. Clusters corresponding to doublets and low QC cells were further excluded from the analysis. c, UMAP representations coloured by sample ID and donor ID. d, Dot plot showing log2-transformed expression of selected genes that distinguish the main cell populations. uSMC = uterine smooth muscle cell; PV = perivascular; eS = non-decidualised endometrial stromal cells; snRNA-seq = single-nuclei RNA sequencing.

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