Fig. 1: Genetic loci from COVID-19 GWAS in peer-reviewed publications to date.
From: Understanding COVID-19 through genome-wide association studies
The loci represent a mixture of risk variants for SARS-CoV-2 infection (blue upward arrows) and severe COVID-19 with complications (red downward arrows). With increasing sample sizes, further loci are likely to emerge. Nominally significant associations at 3q12 and 6p21.1 in the Horowitz et al.5 analysis are not indicated due to substantial sample overlap with the COVID-19 HGI report. N/A indicates that the major histocompatibility complex (MHC) on chromosome 6 was omitted from the reporting in this article due to high heterogeneity of putative associations from the individual studies in the meta-analysis. COVID-19 HGI, COVID-19 Host Genetics Initiative (https://www.covid19hg.org/).
