Extended Data Fig. 3: Manhattan plots for trans-ancestry meta-analyses of European (EUR), Admixed Amerindian (LAT), Admixed African-European (AA) cohorts in eight phenotypes. | Nature Genetics

Extended Data Fig. 3: Manhattan plots for trans-ancestry meta-analyses of European (EUR), Admixed Amerindian (LAT), Admixed African-European (AA) cohorts in eight phenotypes.

From: Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects

Extended Data Fig. 3

Chromosomal position is represented on the x axes and -log10(P-values) on the y axes. P-values are two-sided and based on an inverse-variance-weighted fixed-effects meta-analysis. Blue dashed lines are drawn at the suggestive significance threshold of P = 1 × 10-5 and red dashed lines at the genome-wide significance threshold of P = 5 × 10-8. The phenotypes are: (a) Positive/Negative, (b) Positive/Unscreened, (c) Hospitalized/Not_Hospitalized, (d) Hospitalized/Unscreened, (e) Exposed_Positive/Exposed_Negative, (f) Unscreened/Exposed_Negative, (g) Symptomatic/Paucisymptomatic, and (h) Continuous_Severity_Score.

Back to article page