Extended Data Fig. 9: H3K27ac ensemble contact enrichment and CAGE expression patterns of gene classes separated by SOM. | Nature Genetics

Extended Data Fig. 9: H3K27ac ensemble contact enrichment and CAGE expression patterns of gene classes separated by SOM.

From: Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

Extended Data Fig. 9

a, Controls for contact enrichment around H3K27ac ensembles. All regions were downsampled to n=56 to match the number of 50 kb - 150 kb size ensembles. Labels are as in Fig. 7g. The controls included random positions within the same TAD (a), random positions within TADs without ensembles, and 10MB shifted positions, for GRB TADs (top row) and non-GRB TADs (bottom row). The controls include published data for the Prim-5 stage, as well as new, unpublished data with higher resolution (Prim 5). b, CAGE expression patterns of gene classes separated by SOM. Bar plots in the middle show the proportion of ensemble-associated and GRB genes in each class respectively.

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