Extended Data Fig. 7: Sharing of QTLs across ancestries and tissues. | Nature Genetics

Extended Data Fig. 7: Sharing of QTLs across ancestries and tissues.

From: A multi-tissue atlas of regulatory variants in cattle

Extended Data Fig. 7

(a) Distribution of minor allele frequency (MAF) of loci with bos taurus specific (n = 202,583) and overlapped (n = 459) cis-eQTLs in bos indicus population. (b) Distribution of MAF of loci with bos indicus specific (n = 437) and overlapped cis-eQTLs in bos taurus population. (c) Tissue-sharing patterns of cis-sQTL. (d) The gene co-expression patterns across tissues. (e) The co-splicing patterns of spliced introns across tissues. The π1 values are calculated to measure the replication rates between tissues. (f) The Pearson’s correlation of π1 values of matched tissue-pairs (that is, values in the tissue-sharing heatmaps above) across four data types. The P value is obtained by the two-sided Student’s t-test.

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