Extended Data Fig. 4: GWAS association with different classes of enhancers.
From: Population-level variation in enhancer expression identifies disease mechanisms in the human brain
a. Stratified LD score regression of different classes of enhancers across different classes of traits. A positive coefficient signifies enrichment in heritability (per base enrichment, mean ± standard error).’·’: Nominally significant (P < 0.05);’+’: significant after FDR (Benjamini & Hochberg) correction (FDR < 0.05). b, coverage (Mb) and numbers (k) of different classes of enhancers. c, Stratified LD score regression of cell-type-specific enhancers defined by TEns, the intersection of differential H3K27ac and noncoding OCR (Diff H3K27ac ∩ OCR), and the intersection of differential noncoding OCR and H3K27ac (Diff OCR ∩ H3K27ac) across different classes of traits as in a. d, coverage (Mb), and numbers (k) of the three types of enhancers.
