Extended Data Fig. 1: Quantile-quantile plots for STAAR-O tests P values for four exemplary binary phenotypes with different case–control ratios in the UKBB WES data.
From: SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests
The STAAR-O tests were performed for 18,372 genes with missense and loss-of-function (LoF) variants with three different maximum MAF cutoffs (1%, 0.1%, and 0.01%).
