Extended Data Fig. 5: Haplotype-level association test at the IL6R locus. | Nature Genetics

Extended Data Fig. 5: Haplotype-level association test at the IL6R locus.

From: Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Extended Data Fig. 5

Haplotype-level association results at the IL6R locus. We defined haplotypes as shown in the table, and we estimated the dosage of four haplotypes using phased imputed genotype data. We conducted multivariate logistic regression tests in each of EUR cohorts (n = 97,173 in total), and the results were meta-analyzed using the inverse-variance weighted fixed effect model. The effect size estimate and 2 x s.e. are shown in the right panel.

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