Extended Data Fig. 4: Comparison of the magnitude of the genetic effect on lifespan across conditions.
From: Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila
(A) Across all tested sites, there is a strong correlation between the magnitude of the genetic effect on lifespan estimated on a CTRL diet (x-axis) versus a HS diet (y-axis). The R and p-value from a Pearson correlation are reported on the plot. The plot was created using the “smoothScatter” function in R with default parameters. (B) For sites with significant genetic effects on lifespan that are shared between conditions (shared) or stronger in the HS environment (GxE), the magnitude of the lifespan effect tends to be larger on a HS diet.
