Extended Data Fig. 3: ELISpot results for individual DeepNeoII(+) peptides.

For each murine tumor model, DeepNeoII(+) epitopes that passed thresholds were tested for their ability to stimulate immune responses in vivo. Colored dots indicate individual mice in which the epitopes were tested. Negative control is marked as the red dashed line, and positive control is plotted in the last column. The experiments were individually plotted with a, the first set of experiments on EMT6, n = 29 peptides examined over n = 188 independent experiments b, the second set of experiments on EMT6, which was conducted for n = 19 peptides examined over n = 114 independent experiments c, LLC1, which was conducted for n = 12 peptides examined over n = 72 independent experiments and d, B16F10, which was conducted for n = 15 peptides over n = 90 independent experiments. In all boxplots, center bar represents median box represent 25th and 75th percentile, and whiskers represent furthest outlier ≤1.5× the interquartile range from the box. Outliers of the boxplots are replaced with the actual data point represented as colored dots.