Extended Data Fig. 6: Distribution of EndoFb in hearts at 28 days post TAC. | Nature Genetics

Extended Data Fig. 6: Distribution of EndoFb in hearts at 28 days post TAC.

From: Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis

Extended Data Fig. 6

a, Schematic diagram showing the experimental strategy. b, Whole-mount bright-field and fluorescent views of hearts collected from Nfatc1-Dre;Col1a2-CreER;R26-RL-GFP mice at 28d post sham or TAC. c, Sirius Red staining images showing the fibrotic area on heart sections collected from mice post TAC 28 days. d, Immunostaining for PDGFRa, Vimentin, aSMA, and GFP on whole heart sections. e-g, Immunostaining for PDGFRa (e), Vimentin (f), aSMA (g), with EdU and GFP on VS and LV of the heart sections. Scale bars: yellow, 1 mm; white, 100 µm. Each image is representative of five individual mouse samples.

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