Extended Data Fig. 2: SSIM and SN correlate with genomic coverage and insulation score variance.
From: Reply to: Revisiting the use of structural similarity index in Hi-C
a, Pearson’s correlations of SSIM and SN profiles from the DLBCL-control comparison with genomic coverage of the Hi-C datasets and the variance of the insulation score in the 2 Mb window used for the CHESS analysis. b, Overall SSIM distributions derived from comparisons of GM12878 and K562 Hi-C data from Rao et al. 2014. In all cases GM12878 biological replicate 1 was used as the reference dataset for the CHESS comparisons. This sample has 1.8 billion valid pairs. Point and lines show mean ± one standard deviation across 592-603 2 Mb windows with valid SSIM values. c, Overall SN distributions for the same comparisons as in B. Point and lines show mean ± one standard deviation across 592-603 2 Mb windows with valid SSIM values.
