Extended Data Fig. 5: Regions of interest identified from different biological replicates have significant overlap.
From: Reply to: Revisiting the use of structural similarity index in Hi-C

a, UpSet plot20,21 showing overlap between regions of interest identified from different pairwise comparisons between individual biological replicates of GM12878 and K562. Left, Number of regions passing thresholds in each comparison. Bottom right, intersections between region sets are indicated by linked dots. Top right, interaction size is indicated by the height of the bar. b, The overlap between regions of interest from different comparisons is highly significant (Two-sided Fisher’s exact test p-value and estimated odds ratio).