Table 1 Effect sizes across loci for PPH, endometriosis and uterine fibroids
From: Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage
CHR | BP (hg38) | RSID | Effect allele | Other allele | Effect allele Frequency | Odds ratio (95% CI, P value) | ||
|---|---|---|---|---|---|---|---|---|
PPH | Endometriosis | Uterine fibroids | ||||||
4 | 173807552 | rs13141656 | T | C | 0.30 | 1.10 (1.08–1.13; 1.42 × 10−17) | 0.98 (0.96–1.0; 0.014) | 0.98 (0.96–0.99; 0.00076) |
6 | 143642758 | rs12195857 | A | G | 0.32 | 1.10 (1.08–1.13, 9.86 × 10−17) | 0.97 (0.95–0.99; 0.0022) | 0.97 (0.96–0.98; 2.8 × 10−5) |
10 | 31660483 | rs11591307 | A | G | 0.22 | 1.08 (1.05–1.11, 1.3 × 10−9) | 1.03 (1.03–1.05; 0.015) | 0.94 (0.93–0.95; 4.6 × 10−16) |
12 | 114656455 | rs11067228 | G | A | 0.42 | 1.07 (1.05–1.10, 4.33 × 10−11) | 0.96 (0.95–0.98; 2.8 × 10−5) | 1.00 (0.99–1.02; 0.74) |
X | 132131995 | rs2747025 | A | G | 0.32 | 0.91 (0.89–0.94, 9 × 10−15) | 0.93 (0.91–0.95; 1.2 × 10−14) | 1.17 (1.15–1.18; 4.6 × 10−113) |
