Extended Data Fig. 9: Change in RNA subtype probabilities over time. | Nature Genetics

Extended Data Fig. 9: Change in RNA subtype probabilities over time.

From: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Extended Data Fig. 9

RNA subtype probabilities for the 71 serial patients with RNA-seq data at two or more time points. All patients classified in the low-purity subtype at baseline have a discernable RNA subtype other than low purity at progression, supporting the observation that this subtype is driven by sample purity. Shifts from a non-PR baseline subtype to a largely PR subtype or partial population of PR cells are evident.

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