Fig. 4: RNA subtypes and significantly associated LOF and GOF events. | Nature Genetics

Fig. 4: RNA subtypes and significantly associated LOF and GOF events.

From: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Fig. 4

The location and proximity of individual genes are shown next to each gene with the alternating gray and black bars illustrating when the chromosomal location changes, while black bars directly to the right denote contiguous genes. LOF and GOF features that are significantly enriched or depleted within a specific RNA subtype are highlighted. Enrichment analysis was conducted using a two-tailed Fishers test, and the Benjamini–Hochberg test correction was used for multiple testing to compute a positive false discovery rate (pFDR) value. Genes are only included when pFDR ≤ 0.1, P < 0.05.

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