Extended Data Fig. 2: Copy number consensus clustering matrix.

Consensus clustering matrix with an optimal clustering solution of K = 8. The M3C (Monte Carlo reference-based) consensus clustering algorithm was applied to the CN measurements of 26,771 (100 Kb) intervals across the GRCh37 reference genome for 871 WGS BM-derived baseline samples. Five of the eight subtypes include only samples classified as hyperdiploid.