Extended Data Fig. 8: Epithelial detachment on a serial section that did not undergo Xenium processing. | Nature Genetics

Extended Data Fig. 8: Epithelial detachment on a serial section that did not undergo Xenium processing.

From: Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis

Extended Data Fig. 8

To verify that the epithelial detachment feature was not an artifact of Xenium processing, we took serial sections approximately 45 µm from the processed tissue section. H&E stains, shown here for sample VUILD48LA (NSIP diagnosis), show areas of epithelial detachment are present on both the original section (a,b) and the section that did not undergo Xenium processing (c,d). b and d show the areas marked with boxes in a and c, respectively. Brackets denote epithelial detachment. Scale bars represent 50 µm.

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