Extended Data Fig. 6: Visualization of cellular abundance and cohabitation patterns in healthy and HCC liver tissues.
From: Quantitative characterization of tissue states using multiomics and ecological spatial analysis
(A) Circos plots illustrate cellular abundance and cohabitation frequencies in whole tissue. Nodes represent distinct cell types and edges cohabitation relationships. Node size corresponds to cell-type abundance, while edge thickness denotes cohabitation strength. (B) Analysis focused on the identified diversity hot spots, with green edges highlighting cohabitation patterns unique to these regions. These cohabitation relationships, while not significantly different between healthy and HCC in whole-tissue analysis (two-sided Welch’s t-test with BH correction for FDR control), emerged as distinctive features within hot spots.
