Fig. 3: Phylogenetic trees and mutational signatures across a range of normal and chemotherapy-exposed individuals.
From: The long-term effects of chemotherapy on normal blood cells
Phylogenies were constructed using shared mutation data and the algorithm MPBoot (Methods). Branch lengths correspond to SBS burdens (x axes). A stacked bar plot represents the signatures contributing to each branch, with the color code below the trees. SBSUnassigned indicates mutations that could not confidently be assigned to any reported signature. Drugs in parentheses are those received by the individual at the same time but not believed to be the mutagenic agents.
