Extended Data Fig. 3: Indel signatures that are present in normal and chemotherapy exposed blood.
From: The long-term effects of chemotherapy on normal blood cells
a, Three indel signatures (ID1/2, ID3/5/9, IDA) were extracted by sigHDP. The context on the x-axis show the contributions of different types of indels, grouped by whether variants are deletions or insertions, the size of the event, the presence within repeat units and the sequence content of the indel. b, The proportion of indels and indels burden per mutational signatures across 22 chemotherapy exposed and 9 normal individuals, extracting using msigHDP (Methods). Each column represents samples from one individual. Signatures with the contribution <5% are considered as ‘unassigned’.
