Fig. 6: Phylogenetic relationships between post-treatment HSPCs and corresponding t-MN samples.
From: Clonal evolution of hematopoietic stem cells after autologous stem cell transplantation
a, Integrated phylogenetic tree for PID0002 highlighting the MRCA pinpointed to a clone with concurrent TET2, TP53 mutations and 17p LOH. b, Integrated phylogenetic tree for PID0005 where MRCA was identified in TP53 and DNMT3A-mutated clone. c, Integrated phylogenetic tree for PID0006 where the MRCA is identified within a clone possessing a TP53 mutation. d, Integrated phylogenetic tree for PID0008 with the MRCA traced to a TP53-mutated clone. e, Integrated phylogenetic tree for PID0010 showing the MRCA located at a branching point preceding the acquisition of a U2AF1 mutation.
