Extended Data Fig. 2: Docking simulation of SttH and RebH with indole.
From: Production of Tyrian purple indigoid dye from tryptophan in Escherichia coli
a, SttH (PDB ID: 5HY5) with indole. b, RebH (PDB ID: 2OAL) with indole. The distances between the catalytic residues (Lys and Glu) and the specific carbons (C2, C3, or C6) of the indole ring are indicated, respectively. The catalytic residues (that is lysine and glutamate) of SttH were closer to C6 than the other carbons of indole, and those of RebH were closer to C2 and C3. These results could explain the regioselectivities of the brominated indoles generated by SttH and RebH.
