Extended Data Fig. 10: YY1-G4 binding participates in transcription regulation of EHD3 genes through long-range DNA looping.
From: YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression
a, Read enrichments obtained from BG4 ChIP-seq and YY1 ChIP-Seq experiments. b, Normalized interaction frequency between the two sites linked with a red arch in a in HEK293T cells with or without PDS/TMPyP4 treatment, as captured by YY1 HiChIP. c, Quantification results for the mRNA expression levels of EHD3 genes in HEK293T cells after knockdown of YY1 and/or with PDS/TMPyP4 treatment. The data represent mean ± S.E.M. of results from three independent experiments.
