Extended Data Fig. 3: Zinc finger domain of YY1 is essential, but not sufficient for the specific binding toward G4 structure.
From: YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression
a, A schematic diagram depicting the domain structure of YY1 protein. b-e, Fluorescence anisotropy for monitoring the bindings of mutant (YY1C360S) and truncated (YY11-382, YY1231-414, and YY1293-414) YY1 proteins with hTEL G4 and the corresponding M4 DNA probes. The data represent the mean ± S.E.M. of results obtained from 3 independent experiments.
